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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
14.5 DPC

5 matching records from 5 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Sirt1  sirtuin 1   (Synonyms: Sir2, Sir2alpha)
Results  Reference
1J:223236 Di Sante G, Wang L, Wang C, Jiao X, Casimiro MC, Chen K, Pestell TG, Yaman I, Di Rocco A, Sun X, Horio Y, Powell MJ, He X, McBurney MW, Pestell RG, Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration. Mol Endocrinol. 2015 Feb;29(2):200-12
1J:138789 Hasegawa K, Yoshikawa K, Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons. J Neurosci. 2008 Aug 27;28(35):8772-84
1J:248208 Hisahara S, Chiba S, Matsumoto H, Tanno M, Yagi H, Shimohama S, Sato M, Horio Y, Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15599-604
1*J:172620 Ogawa T, Wakai C, Saito T, Murayama A, Mimura Y, Youfu S, Nakamachi T, Kuwagata M, Satoh K, Shioda S, Distribution of the longevity gene product, SIRT1, in developing mouse organs. Congenit Anom (Kyoto). 2011 Jun;51(2):70-9
1*J:87352 Sakamoto J, Miura T, Shimamoto K, Horio Y, Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain. FEBS Lett. 2004 Jan 2;556(1-3):281-6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory